New
Hindi Medium: (Delhi) - GS Foundation (P+M) : 10th Aug 2026, 3:00 PM Hindi Medium: (Prayagraj) - GS Foundation (P+M) : 18th Aug 2026, 8:00 AM English Medium: (Delhi) - GS Foundation (P+M) : 6th Aug 2026 English Medium: (Prayagraj) - GS Foundation (P+M) : 15th July 2026, 8:00 AM Hindi Medium: (Delhi) - GS Foundation (P+M) : 10th Aug 2026, 3:00 PM Hindi Medium: (Prayagraj) - GS Foundation (P+M) : 18th Aug 2026, 8:00 AM English Medium: (Delhi) - GS Foundation (P+M) : 6th Aug 2026 English Medium: (Prayagraj) - GS Foundation (P+M) : 15th July 2026, 8:00 AM

Current Affairs for 18 July 2026

India Approves Novo Nordisk’s Wegovy for Fatty Liver Disease (MASH): Key Features, Benefits & Significance

Prelims

Science & Technology (Health) + Current Affairs 

Mains

GS Paper II (Health) 

GS Paper III (Science & Technology)

Why in News ?

India's drug regulator, the Central Drugs Standard Control Organisation (CDSCO), has approved Novo Nordisk's Wegovy (Semaglutide 2.4 mg injection) for the treatment of Metabolic Dysfunction-Associated Steatohepatitis (MASH), a serious form of fatty liver disease.

What is MASH (Metabolic Dysfunction-Associated Steatohepatitis) ?

  • MASH is a serious and progressive form of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD).
  • It occurs due to excess fat accumulation in the liver, accompanied by inflammation and liver cell damage.
  • If left untreated, it may progress to :
    • Liver fibrosis
    • Cirrhosis
    • Liver failure
    • Hepatocellular carcinoma (Liver cancer)

Risk Factors of MASH

  • Obesity : Excess body weight increases the accumulation of fat in the liver, making obesity one of the major risk factors for MASH.
  • Type-2 Diabetes : People with Type-2 diabetes are at a significantly higher risk of developing MASH due to insulin resistance and abnormal fat metabolism.
  • Metabolic Syndrome : Conditions such as high blood sugar, high blood pressure, abnormal cholesterol levels, and excess abdominal fat collectively increase the risk of MASH.
  • High Cholesterol : Elevated levels of cholesterol and triglycerides promote fat deposition in the liver, contributing to the development and progression of MASH.
  • Sedentary Lifestyle : Lack of regular physical activity increases the likelihood of obesity and metabolic disorders, thereby raising the risk of developing MASH.

Symptoms of MASH

  • MASH is often referred to as a "silent disease" because many people do not experience noticeable symptoms until the disease has progressed to an advanced stage and significant liver damage has occurred.
  • The possible symptoms include :
    • Fatigue: Patients may experience persistent tiredness and a lack of energy.
    • Weakness: Generalized weakness and reduced physical stamina are common.
    • Pain in the Upper Right Abdomen: Some individuals may feel discomfort or pain in the upper right side of the abdomen, where the liver is located.
    • Unexplained Weight Loss : In advanced stages of the disease, patients may experience unintended weight loss due to progressive liver damage.

What is Wegovy ?

Particular

Details

Generic Name

Semaglutide

Brand Name

Wegovy

Manufacturer

Novo Nordisk (Denmark)

Drug Class

GLP-1 Receptor Agonist

Administration

Once-weekly injection

Approved by CDSCO for

MASH and Chronic Weight Management

How Does Wegovy Work ?

  • Semaglutide acts as a GLP-1 (Glucagon-Like Peptide-1) receptor agonist.
  • It helps by :
    • Reducing appetite
    • Increasing satiety (feeling of fullness)
    • Promoting weight loss
    • Improving insulin sensitivity
    • Reducing liver fat accumulation
    • Decreasing liver inflammation

Why is this Approval Important ?

  • Rising prevalence of obesity and diabetes in India.
  • Increasing burden of fatty liver disease.
  • MASH has limited approved treatment options.
  • Early treatment can prevent severe liver complications.

About Novo Nordisk

  • Danish multinational pharmaceutical company.
  • Headquarters: Bagsværd, Denmark
  • Known for :
  • Diabetes medicines
  • Obesity drugs
    • GLP-1 therapies

About the Central Drugs Standard Control Organisation (CDSCO)

  • The Central Drugs Standard Control Organisation (CDSCO) is India's National Drug Regulatory Authority, responsible for regulating pharmaceuticals and medical devices to ensure that they are safe, effective, and of high quality.

Functions of CDSCO

  • Approves New Drugs and Vaccines : CDSCO grants approval for the manufacture, import, and marketing of new drugs and vaccines after evaluating their safety, efficacy, and quality.
  • Regulates Clinical Trials : It oversees and regulates clinical trials conducted in India to ensure ethical standards and participant safety.
  • Ensures Quality, Safety, and Efficacy : CDSCO monitors the quality, safety, and effectiveness of medicines, medical devices, and cosmetics available in the country.
  • Coordinates with State Drug Authorities : It works in coordination with State Drug Control Organisations to ensure uniform enforcement of the Drugs and Cosmetics Act, 1940.

Administrative Ministry

  • The CDSCO functions under the Ministry of Health and Family Welfare, Government of India.

Head of CDSCO

  • The organisation is headed by the Drugs Controller General of India (DCGI), who is responsible for approving new drugs, regulating clinical trials, and enforcing drug standards across the country.

Prelims Question

Q. With reference to Wegovy, consider the following statements:

  1. Wegovy contains Semaglutide as its active ingredient.
  2. It belongs to the GLP-1 Receptor Agonist class of drugs.
  3. It has been approved in India for the treatment of MASH and chronic weight management.

Which of the statements given above is/are correct?

  1. 1 and 2 only
  2. 2 and 3 only
  3. 1 and 3 only
  4. 1, 2 and 3 

Mains Practice Question

Q. The rising burden of obesity and metabolic disorders has increased the prevalence of fatty liver disease in India. Discuss the significance of the approval of Wegovy (Semaglutide) for the treatment of MASH. Also examine the challenges in managing non-communicable diseases (NCDs) in India.

FAQs: India Approves Wegovy for MASH (Fatty Liver Disease)

Q1. What is Wegovy ?

Answer : Wegovy is a once-weekly injectable medicine containing Semaglutide, a GLP-1 Receptor Agonist developed by Novo Nordisk. It is used for chronic weight management and has now been approved in India for the treatment of MASH.

Q2. What is MASH ?

Answer : Metabolic Dysfunction-Associated Steatohepatitis (MASH) is a serious form of fatty liver disease in which excess fat accumulates in the liver, causing inflammation and liver cell damage. If left untreated, it can progress to fibrosis, cirrhosis, liver failure, or liver cancer.

Q3. Which authority approved Wegovy in India ?

Answer : Wegovy was approved by the Central Drugs Standard Control Organisation (CDSCO), India's national drug regulatory authority.

Q4. Which company manufactures Wegovy ?

Answer : Wegovy is manufactured by Novo Nordisk, a Danish pharmaceutical company specializing in diabetes, obesity, and metabolic disease treatments.

Q5. What is the active ingredient in Wegovy ?

Answer : The active ingredient in Wegovy is Semaglutide, a GLP-1 Receptor Agonist.

MH-60R Seahawk Helicopter: Features, India's Procurement, Strategic Importance & India-US Defence Partnership

Keywords

MH-60R Seahawk, Lockheed Martin, Sikorsky Aircraft, Indian Navy, Anti-Submarine Warfare (ASW), Anti-Surface Warfare (ASuW), Maritime Domain Awareness (MDA), Foreign Military Sales (FMS), Indo-Pacific, Indian Ocean Region (IOR)

Focus Area

Mains GS II (International Relations) India–US Strategic Partnership, Defence Cooperation, Indo-Pacific Strategy, Quad Mains

GS III (Internal Security & Defence) Maritime Security, Naval Modernisation, Defence Technology, Anti-Submarine Warfare

Why in News ?

The Indian Navy has received another MH-60R Seahawk multi-role naval helicopter from the United States, which arrived at INS Garuda, Kochi.

MH-60R Seahawk

  • The MH-60R Seahawk is the world's most advanced multi-mission maritime helicopter, manufactured by Lockheed Martin (Sikorsky Aircraft) for the United States Navy and allied countries.
  • It is designed to perform a wide range of naval missions, including Anti-Submarine Warfare (ASW), Anti-Surface Warfare (ASuW), Intelligence, Surveillance and Reconnaissance (ISR), Search and Rescue (SAR), Electronic Warfare, Special Operations Support, and Maritime Interdiction.
  • The helicopter is equipped with state-of-the-art airborne dipping sonar, sonobuoys, multi-mode maritime radar, Forward Looking Infrared (FLIR), electronic support measures, data links, and advanced mission computers, enabling it to detect, track, and engage enemy submarines and surface vessels over long distances.
  • It can operate from aircraft carriers, destroyers, frigates, and shore-based naval air stations, making it one of the most versatile helicopters in modern naval warfare.

Anti-Submarine Warfare (ASW)

Anti-Submarine Warfare refers to military operations conducted to detect, track, monitor, deter, and destroy enemy submarines. With the growing presence of conventional and nuclear submarines in the Indian Ocean, ASW has become one of the Indian Navy's highest operational priorities. The MH-60R significantly strengthens India's underwater warfare capability through its advanced sonar systems, sonobuoys, and lightweight torpedoes.

Anti-Surface Warfare (ASuW)

Anti-Surface Warfare involves detecting and neutralising enemy warships, patrol vessels, and other surface combatants. The MH-60R carries AGM-114 Hellfire missiles and advanced targeting systems, enabling precision engagement of hostile vessels while supporting naval task forces.

Foreign Military Sales (FMS)

Foreign Military Sales (FMS) is a US government-to-government defence export programme under which friendly countries procure military equipment, weapons, training, logistics, and support directly from the United States Government. India's purchase of the MH-60R helicopters was concluded through this route, ensuring long-term maintenance, training, and operational support.

India-US Defence Partnership

Over the last decade, India and the United States have transformed their defence relationship into one of the most comprehensive strategic partnerships in the Indo-Pacific. The two countries regularly conduct joint military exercises such as Malabar, Yudh Abhyas, Tiger Triumph, and Cope India, while foundational agreements including LEMOA (2016), COMCASA (2018), BECA (2020), and GSOMIA have enabled greater logistics sharing, secure communications, geospatial intelligence sharing, and defence technology cooperation.

The induction of the MH-60R further enhances interoperability between the Indian Navy and the US Navy during joint operations and humanitarian assistance missions.

About MH-60R Seahawk

Particular

Details

Manufacturer

Lockheed Martin (Sikorsky Aircraft)

Country of Origin

United States

Type

Multi-role Naval Helicopter

Operators

US Navy, Indian Navy and several allied countries

Engines

Twin General Electric T700 Turboshaft Engines

Crew

4

Maximum Speed

Around 270 km/h

Operational Range

Approximately 830 km

Maximum Endurance

About 4 hours

Platform

Aircraft Carriers, Destroyers, Frigates and Naval Air Stations

Major Sensors and Weapons

Sensors

  • AN/AQS-22 Airborne Low Frequency Dipping Sonar
  • Sonobuoy Launch System
  • APS-153 Multi-Mode Maritime Radar
  • Forward Looking Infrared (FLIR)
  • Electronic Support Measures (ESM)
  • Identification Friend or Foe (IFF)
  • Secure Tactical Data Links

Weapons

  • Mk-54 Lightweight Torpedoes
  • AGM-114 Hellfire Missiles
  • 12.7 mm Machine Guns
  • Precision-guided weapons for maritime strike missions

India's MH-60R Procurement

Particular

Details

Contract Signed

2020

Total Helicopters Ordered

24

Procurement Route

Foreign Military Sales (FMS)

Estimated Cost

Approximately US$2.6 Billion

Delivery Status

Deliveries underway

Primary Purpose

Replace ageing Sea King helicopters

Strategic Importance for India

1. Strengthening Anti-Submarine Warfare

China has significantly expanded the deployment of both conventional and nuclear-powered submarines in the Indian Ocean Region. The MH-60R provides India with a modern airborne ASW platform capable of detecting and neutralising underwater threats before they approach Indian naval assets.

2. Maritime Domain Awareness (MDA)

The helicopter's advanced radar and surveillance systems enable continuous monitoring of India's vast Exclusive Economic Zone (EEZ), critical Sea Lines of Communication (SLOCs), offshore energy infrastructure, and strategic maritime chokepoints.

3. Protection of Carrier Battle Groups

The MH-60R serves as the "eyes and ears" of naval fleets by extending the surveillance range of aircraft carriers and destroyers. It protects carrier strike groups from submarine attacks and enhances fleet air defence.

4. Countering Chinese Presence in the Indian Ocean

China's increasing naval deployments, including research vessels, intelligence ships, and submarines, have made underwater surveillance a strategic necessity. The Seahawk strengthens India's capability to maintain maritime superiority across the Indian Ocean Region.

5. Enhancing Network-Centric Warfare

The helicopter integrates seamlessly with modern Indian warships through secure communication links, enabling real-time intelligence sharing and coordinated maritime operations.

6. Humanitarian Assistance and Disaster Relief (HADR)

Apart from combat missions, the MH-60R can undertake medical evacuation, disaster relief, search and rescue operations, and evacuation of civilians during natural disasters.

Significance for India-US Relations

  • Deepens strategic trust between the two democracies.
  • Enhances defence interoperability in the Indo-Pacific.
  • Supports Quad maritime cooperation.
  • Improves joint naval exercises like Malabar.
  • Demonstrates the growing defence technology partnership.
  • Contributes to maintaining a free, open, and inclusive Indo-Pacific.

Challenges

  • High lifecycle and maintenance costs.
  • Dependence on imported defence platforms.
  • Requirement for specialised crew training.
  • Long-term logistics and spare parts support.
  • Need for greater indigenous capability under Aatmanirbhar Bharat.

Prelims MCQ

Q. With reference to the MH-60R Seahawk helicopter, consider the following statements:

  1. It is manufactured by Lockheed Martin's Sikorsky division.
  2. It is capable of Anti-Submarine Warfare and Anti-Surface Warfare.
  3. India procured the helicopters through the Foreign Military Sales (FMS) programme of the United States.
  4. It is developed exclusively for operations from aircraft carriers and cannot operate from destroyers.

Which of the statements given above are correct?

(a) 1 and 2 only
(b) 2, 3 and 4 only
(c) 1, 2 and 3 only
(d) 1, 3 and 4 only

Mains Practice Question

"The induction of advanced naval aviation platforms like the MH-60R Seahawk represents a paradigm shift in India's maritime security architecture." Discuss the strategic significance of the MH-60R helicopters in strengthening India's naval capabilities and examine their role in deepening India-US defence cooperation.

FAQs

1. What is the MH-60R Seahawk ?

The MH-60R Seahawk is an advanced multi-role naval helicopter developed by Lockheed Martin (Sikorsky) for missions such as anti-submarine warfare, anti-surface warfare, maritime surveillance, search and rescue, and special operations support.

2. Why is the MH-60R important for the Indian Navy ?

It significantly enhances India's ability to detect enemy submarines, protect naval fleets, improve maritime domain awareness, and safeguard strategic interests in the Indian Ocean Region.

3. How many MH-60R helicopters has India ordered ?

India signed a US$2.6 billion contract in 2020 to procure 24 MH-60R Seahawk helicopters from the United States under the Foreign Military Sales (FMS) programme.

4. Which Indian naval platforms will operate the MH-60R ?

The helicopter can operate from INS Vikrant, INS Vikramaditya, Kolkata-class destroyers, Visakhapatnam-class destroyers, Nilgiri-class frigates, and other modern frontline warships equipped with helicopter facilities.

5. How does the MH-60R strengthen India-US defence cooperation ?

Its induction enhances interoperability between the Indian and US Navies, supports joint exercises like Malabar, promotes advanced defence technology collaboration, and reinforces the shared vision of a free, open, and rules-based Indo-Pacific.

Nasha Mukt Bharat Abhiyaan Reaches 29.32 Crore Citizens: India's Drug-Free Mission Gains Nationwide Momentum

Keywords

Drug Demand Reduction • Community Participation • Jan Andolan • Social Reintegration • Harm Reduction • Whole-of-Government Approach • Public Health • Youth Empowerment • Evidence-Based Policy • Rehabilitation • Behavioural Change Communication • Internal Security • Preventive Healthcare

Focus Area

GS-I : Social Issues, Youth, Substance Abuse

GS-II : Welfare Schemes, Health Governance, Vulnerable Sections

GS-III : Internal Security, Drug Trafficking, Border Management, Organized Crime.

Why in News ?

The Ministry of Social Justice and Empowerment has announced that the Nasha Mukt Bharat Abhiyaan (NMBA) has reached over 29.32 crore citizens across India through awareness campaigns and community participation. Since its launch in 2020, the campaign has expanded from 272 vulnerable districts to all districts of the country, making it one of India's largest social awareness initiatives against substance abuse.

What is Nasha Mukt Bharat Abhiyaan (NMBA)?

Nasha Mukt Bharat Abhiyaan (NMBA) is the flagship anti-drug awareness and rehabilitation campaign of the Ministry of Social Justice and Empowerment.

Objectives

  • Prevent substance abuse through awareness.
  • Reduce demand for narcotic drugs.
  • Promote early intervention and counselling.
  • Expand treatment and rehabilitation facilities.
  • Ensure social reintegration of recovered addicts.
  • Encourage community participation against drug abuse.
  • Build a healthy and productive youth population.

The campaign adopts an evidence-based approach, focusing equally on prevention, treatment and rehabilitation instead of relying solely on law enforcement.

Major Achievements of NMBA (July 2026)

Indicator

Achievement

Citizens Reached

29.32 crore+

Youth Covered

11.20 crore+

Women Covered

7.92 crore+

Awareness Activities

21 lakh+

Educational Institutions Covered

Schools, Colleges & Universities nationwide

Drug De-addiction Helpline Calls (14446)

4.60 lakh+

People Benefitted through Rehabilitation Services

28.29 lakh+

Treatment Centres Supported

768

Increase in Persons Seeking Treatment

294% growth (2020-2025)

Treatment & Rehabilitation Infrastructure under NAPDDR

The Ministry has significantly expanded treatment and rehabilitation services across the country.

Institutional Network

  • Integrated Rehabilitation Centres for Addicts (IRCAs)
  • Community-based Peer-led Intervention Centres (CPLIs)
  • Outreach and Drop-in Centres (ODICs)
  • Addiction Treatment Facilities (ATFs)

Together, these facilities have benefited over 28.29 lakh individuals.

A notable achievement is the 294% increase in treatment seekers, from 2.08 lakh in 2020 to over 8.20 lakh in 2025, indicating greater awareness and trust in rehabilitation services.

NMBA App 2.0

To strengthen implementation, the Government launched NMBA App 2.0.

Features

  • Real-time reporting of awareness activities
  • Monitoring by States and Districts
  • Digital campaign tracking
  • Citizen participation features
  • Better coordination among stakeholders

Drug De-Addiction Helpline – 14446

The Ministry operates the National Drug De-Addiction Helpline (14446).

Services

  • Counselling
  • Psychological support
  • Information on treatment centres
  • Referral services
  • Family guidance

The helpline has received over 4.60 lakh calls, becoming the first point of assistance for people affected by substance abuse.

Nasha Mukti Mitra Initiative

Citizens can voluntarily become Nasha Mukti Mitras after taking the Nasha Mukt Bharat Pledge.

Responsibilities

  • Spread awareness.
  • Encourage healthy lifestyles.
  • Support individuals recovering from addiction.
  • Organise awareness campaigns.
  • Promote community participation.

This initiative aims to transform every citizen into an anti-drug ambassador.

Key Features of NMBA

Feature

Importance

Community Participation

Converts anti-drug efforts into a Jan Andolan

Awareness Campaigns

Prevents first-time drug use through education

Youth-Centric Approach

Targets the most vulnerable age group

Women Participation

Strengthens family and community resilience

Rehabilitation Services

Provides treatment and recovery support

Inter-Ministerial Coordination

Ensures integrated governance

NMBA App 2.0

Enables digital monitoring and transparency

Drug Helpline (14446)

Provides accessible counselling and referral services

Why is NMBA Important ?

1. Social Significance

  • Protects India's demographic dividend.
  • Reduces crime associated with drug abuse.
  • Promotes healthy youth.
  • Reduces social stigma.
  • Strengthens family institutions.

2. Public Health Significance

  • Improves access to addiction treatment.
  • Reduces mental health burden.
  • Supports long-term recovery.
  • Prevents relapse through counselling and rehabilitation.

3. Governance Significance

  • Demonstrates convergence among ministries and states.
  • Strengthens evidence-based policymaking.
  • Supports Sustainable Development Goal (SDG)-3 (Good Health & Well-being).
  • Improves monitoring through digital platforms.

4. Internal Security Significance

Drug trafficking finances organised crime, terrorism and illegal arms trade. Therefore, reducing drug demand also strengthens India's internal security.

Major Challenges

  • Many addicts hesitate to seek treatment due to fear of discrimination.
  • Rehabilitation facilities remain inadequate in remote and rural areas.
  • New Psychoactive Substances (NPS), synthetic opioids and designer drugs are increasingly difficult to detect and regulate.
  • Dark web transactions and encrypted communication have made drug trafficking more sophisticated.
  • Successful recovery requires long-term counselling, employment support and family acceptance.
  • India's proximity to the Golden Crescent and Golden Triangle makes it a major transit and destination country for narcotic drugs.

Government Initiatives Related to Drug Demand Reduction

  • Nasha Mukt Bharat Abhiyaan (NMBA)
  • National Action Plan for Drug Demand Reduction (NAPDDR)
  • Integrated Rehabilitation Centres for Addicts (IRCAs)
  • Community-based Peer-led Intervention Centres (CPLIs)
  • Outreach and Drop-in Centres (ODICs)
  • Addiction Treatment Facilities (ATFs)
  • Drug De-addiction Helpline – 14446
  • NMBA App 2.0
  • National Mental Health Programme (NMHP)
  • Pradhan Mantri Jan Arogya Yojana (PM-JAY)

Way Forward

  • Strengthen real-time drug abuse data systems.
  • Expand rehabilitation centres in underserved districts.
  • Integrate drug prevention education into school curricula.
  • Increase community-based counselling services.
  • Enhance international cooperation against drug trafficking.
  • Use AI, digital platforms and social media for targeted awareness.
  • Promote skill development and employment for recovered addicts.
  • Regularly update legal frameworks to address synthetic drugs and cyber-enabled trafficking.

Prelims MCQ

Q. With reference to the Nasha Mukt Bharat Abhiyaan (NMBA), consider the following statements:

  1. It was launched on 15 August 2020 under the National Action Plan for Drug Demand Reduction (NAPDDR). 
  2. The Ministry of Home Affairs is the nodal ministry for implementing NMBA. 
  3. The campaign initially covered 272 vulnerable districts before being expanded nationwide. 

Which of the statements given above is/are correct?

A. 1 and 2 only
B. 2 and 3 only
C. 1 and 3 only
D. 1, 2 and 3

Mains Practice Question

"Drug abuse is not merely a law-and-order issue but a multidimensional public health and social challenge." Discuss the role of the Nasha Mukt Bharat Abhiyaan in addressing drug demand reduction in India. Also examine the challenges and suggest measures for making India drug-free.

 

FAQs

1. What is the Nasha Mukt Bharat Abhiyaan (NMBA) ?

It is a flagship campaign of the Ministry of Social Justice and Empowerment, launched on 15 August 2020 under NAPDDR to prevent substance abuse through awareness, treatment, rehabilitation and community participation.

2. Which ministry implements the Nasha Mukt Bharat Abhiyaan ?

The Ministry of Social Justice and Empowerment is the nodal ministry responsible for implementing the campaign in coordination with States, the Narcotics Control Bureau, NGOs and educational institutions.

3. What is the Drug De-addiction Helpline 14446 ?

It is a national toll-free helpline that provides counselling, information and referral services to individuals and families affected by substance abuse.

4. What is the Nasha Mukti Mitra Initiative?

It is a volunteer initiative under NMBA where citizens take the Nasha Mukt Bharat Pledge and work as Nasha Mukti Mitras to spread awareness and encourage a drug-free society.

5. Under which programme was NMBA launched ?

The campaign was launched under the National Action Plan for Drug Demand Reduction (NAPDDR), which focuses on prevention, treatment, rehabilitation and social reintegration of persons affected by substance abuse.

upsc english
« »
  • SUN
  • MON
  • TUE
  • WED
  • THU
  • FRI
  • SAT
Have any Query?

Our support team will be happy to assist you!

OR