The Serum Institute of India (SII) has entered into a strategic partnership with the Gates Medical Research Institute (Gates MRI) to manufacture M72/AS01E, a promising tuberculosis (TB) vaccine candidate currently undergoing Phase III clinical trials. If approved, it could become the first new TB vaccine in more than 100 years, after the Bacille Calmette-Guérin (BCG) vaccine.
Partnership Between Serum Institute and Gates MRI
According to estimates by Serum Institute and Gates MRI, a vaccine with similar efficacy could :
Tuberculosis remains one of the world's deadliest infectious diseases.
Major countries with the highest TB burden include :
Unlike COVID-19 vaccines, TB vaccine development has taken decades because :
Developed by : Indian Council of Medical Research (ICMR) ,Cadila Pharmaceuticals
Causative Organism :- Mycobacterium tuberculosis
Mode of Transmission :- Airborne infection through droplets released when an infected person coughs, sneezes, speaks, or sings.
Commonly Affected Organ :- Lungs (Pulmonary TB)
The collaboration between the Serum Institute of India and the Gates Medical Research Institute marks a significant milestone in the global fight against tuberculosis. If the M72/AS01E vaccine successfully completes Phase III trials and secures regulatory approval, it could become the first new TB vaccine in over a century, substantially reducing the global TB burden while reinforcing India's leadership in vaccine innovation, manufacturing, and global public health.
Frequently Asked Questions (FAQs): Serum Institute's M72/AS01E TB VaccineQ1. Why is the M72/AS01E vaccine in the news ?Answer : The Serum Institute of India (SII) has partnered with the Gates Medical Research Institute (Gates MRI) to manufacture M72/AS01E, a promising tuberculosis (TB) vaccine candidate currently in Phase III clinical trials. If approved, it could become the first new TB vaccine in over 100 years. Q2. What is M72/AS01E ?Answer : M72/AS01E is an experimental protein subunit vaccine designed to prevent the progression of latent TB infection into active pulmonary tuberculosis, especially in adults. Q3. Who developed the M72/AS01E vaccine?Answer : The vaccine was originally developed by GlaxoSmithKline (GSK). Later, its development was transferred to the Gates Medical Research Institute (Gates MRI), which is currently conducting Phase III clinical trials. Q :-Tuberculosis is caused by :A. Plasmodium falciparum |
PrelimsCurrent Affairs + International Relations + World Geography + International Organizations. MainsGS Paper-I : World History (Colonialism, Decolonization, and the 1982 Falklands War). GS Paper-II : International Relations (Territorial Disputes, Sovereignty, International Law, and United Nations) GS Paper-IV : Ethics (Political Neutrality in Sports, Freedom of Expression, and Ethical Dilemmas). |
The Falkland Islands (called Islas Malvinas in Argentina) are a group of islands in the South Atlantic Ocean claimed by both Argentina and the United Kingdom.
FIFA and the International Football Association Board (IFAB) prohibit political messages in football.
Yes. Argentina has previously raised the Malvinas issue during football matches.
The Falklands banner controversy highlights how historical and territorial disputes can resurface in international sports. While the Malvinas issue remains deeply connected to Argentina's national identity, FIFA's commitment to political neutrality means such actions may attract disciplinary measures. The final decision by FIFA will determine whether Argentina faces any sanctions.
Prelims Practice QuestionsQ. Consider the following statements regarding the Falklands War (1982):
Which of the statements given above is/are correct?
Mains Practice QuestionsQ. The Falkland (Malvinas) dispute continues to influence diplomatic relations between Argentina and the United Kingdom. Examine the historical background of the dispute and discuss its contemporary geopolitical significance. |
FAQs: The Falklands Banner ControversyQ1. Why is the Falklands Banner Controversy in the news ?Answer : After Argentina defeated England in the 2026 FIFA World Cup semi-final, Argentine players displayed a banner reading "Las Malvinas son Argentinas" ("The Falkland Islands are Argentine"), leading to a political controversy and possible FIFA disciplinary action. Q2. What are the Falkland Islands (Islas Malvinas)?Answer : The Falkland Islands are an archipelago in the South Atlantic Ocean. They are administered by the United Kingdom, but Argentina claims sovereignty over them and refers to them as Islas Malvinas. Q3. Why do Argentina and the United Kingdom dispute the Falkland Islands?Answer : Argentina claims it inherited the islands from Spain after independence in 1816, while the United Kingdom has administered the islands since reasserting control in 1833 and considers its sovereignty legitimate. Q4. What was the Falklands War of 1982?Answer : The Falklands War was a 74-day conflict between Argentina and the United Kingdom after Argentina invaded the islands. Britain regained control, and more than 900 people lost their lives during the war. |
PrelimsCurrent Affairs + International Relations + World Geography + International Organizations. MainsGS Paper-I : World History (Colonialism, Decolonization, and the 1982 Falklands War). GS Paper-II : International Relations (Territorial Disputes, Sovereignty, International Law, and United Nations) GS Paper-IV : Ethics (Political Neutrality in Sports, Freedom of Expression, and Ethical Dilemmas). |
The Falkland Islands (called Islas Malvinas in Argentina) are a group of islands in the South Atlantic Ocean claimed by both Argentina and the United Kingdom.
FIFA and the International Football Association Board (IFAB) prohibit political messages in football.
Yes. Argentina has previously raised the Malvinas issue during football matches.
The Falklands banner controversy highlights how historical and territorial disputes can resurface in international sports. While the Malvinas issue remains deeply connected to Argentina's national identity, FIFA's commitment to political neutrality means such actions may attract disciplinary measures. The final decision by FIFA will determine whether Argentina faces any sanctions.
Prelims Practice QuestionsQ. Consider the following statements regarding the Falklands War (1982):
Which of the statements given above is/are correct?
Mains Practice QuestionsQ. The Falkland (Malvinas) dispute continues to influence diplomatic relations between Argentina and the United Kingdom. Examine the historical background of the dispute and discuss its contemporary geopolitical significance. |
FAQs: The Falklands Banner ControversyQ1. Why is the Falklands Banner Controversy in the news ?Answer : After Argentina defeated England in the 2026 FIFA World Cup semi-final, Argentine players displayed a banner reading "Las Malvinas son Argentinas" ("The Falkland Islands are Argentine"), leading to a political controversy and possible FIFA disciplinary action. Q2. What are the Falkland Islands (Islas Malvinas)?Answer : The Falkland Islands are an archipelago in the South Atlantic Ocean. They are administered by the United Kingdom, but Argentina claims sovereignty over them and refers to them as Islas Malvinas. Q3. Why do Argentina and the United Kingdom dispute the Falkland Islands?Answer : Argentina claims it inherited the islands from Spain after independence in 1816, while the United Kingdom has administered the islands since reasserting control in 1833 and considers its sovereignty legitimate. Q4. What was the Falklands War of 1982?Answer : The Falklands War was a 74-day conflict between Argentina and the United Kingdom after Argentina invaded the islands. Britain regained control, and more than 900 people lost their lives during the war. |
SNFAs may include :
Before the introduction of the SNFA framework, banks occasionally acquired immovable properties while recovering bad loans. However, there was no comprehensive regulatory framework governing how such assets should be valued, managed, accounted for, or disposed of.
This resulted in several issues :
The RBI observed that banks should function primarily as financial intermediaries rather than as owners of large real estate portfolios. Therefore, a uniform prudential framework became necessary.
The new framework aims to :
A bank may acquire an SNFA only when all of the following conditions are satisfied :
Where only part of the outstanding loan is settled through transfer of property :
To prevent inflated asset values and improve transparency, the RBI has prescribed conservative valuation standards.
Every SNFA must be recorded at the lower of the following two values :
This conservative approach ensures :
Every commercial bank must formulate a Board-approved policy governing the acquisition and disposal of SNFAs.
The policy should cover :
The RBI has emphasized that acquisition of immovable property should remain an exceptional recovery measure rather than a regular business activity.
Banks are expected to dispose of SNFAs as quickly as possible.
The RBI has prescribed that :
The objective is to prevent banks from accumulating large portfolios of real estate assets.
The RBI has mandated that disposal should primarily take place through public auctions.
Banks must follow the auction principles prescribed under the SARFAESI Act, 2002.
Public auctions are intended to ensure :
One of the most significant safeguards introduced by the RBI is the prohibition on resale of SNFAs to :
This restriction applies even if the property subsequently ceases to be classified as an SNFA.
The objective is to :
The RBI has clarified that SNFAs will not be treated as :
Similarly, SNFAs will not affect the :
Provisioning Coverage Ratio (PCR)
Instead, banks must disclose them separately in their balance sheets under :
"Non-banking assets acquired in satisfaction of claims."
This ensures better transparency in financial reporting.
Banks must submit annual information on SNFAs through the RBI's Centralised Information Management System (CIMS).
The disclosure should include :
These disclosures will strengthen regulatory oversight and improve market transparency.
The revised framework will:Come into force on 1 October 2026.
For legacy SNFAs already held by banks:Assets existing as on 30 September 2026 must be brought into compliance by 30 September 2027.
Thus, banks have been provided a one-year transition period.
The RBI's SNFA framework is expected to significantly strengthen India's banking sector by :
FAQs: RBI's New Prudential Framework for Specified Non-Financial Assets (SNFAs)Q1. What is the RBI's new SNFA framework ?Answer : The RBI's new Prudential Framework for Specified Non-Financial Assets (SNFAs) provides uniform rules for the acquisition, valuation, management, accounting, disclosure, and disposal of immovable properties acquired by banks from defaulting borrowers. Q2. What are Specified Non-Financial Assets (SNFAs) ?Answer : SNFAs are immovable properties such as residential buildings, commercial properties, industrial land, warehouses, and other real estate acquired by banks in full or partial settlement of loans that have become Non-Performing Assets (NPAs). Q3. Why did the RBI introduce the SNFA framework ?Answer: The framework was introduced to standardise the treatment of immovable assets acquired from defaulting borrowers, improve transparency, strengthen governance, ensure prudent accounting practices, and encourage faster recovery of stressed assets. Q4. When does an asset qualify as an SNFA?Answer : An asset qualifies as an SNFA only after the borrower's loan has been classified as an NPA and the legal title of the immovable property has been transferred to the bank in full or partial settlement of the outstanding loan. Q5. How are SNFAs valued under the new framework ?Answer : Every SNFA must be recorded at the lower of:
Q6. What is the maximum period for banks to hold SNFAs ?Answer : Banks must make all reasonable efforts to dispose of SNFAs at the earliest and are required to sell them within seven years from the date of acquisition. |
McqQ1. With reference to the Reserve Bank of India's new Prudential Framework for Specified Non-Financial Assets (SNFAs), consider the following statements: SNFAs refer to movable assets acquired by banks from defaulting borrowers. SNFAs are acquired only after a borrower's account is classified as a Non-Performing Asset (NPA). A property becomes an SNFA only after its legal title is transferred to the bank. Which of the statements given above is/are correct? A. 1 only B. 2 and 3 only C. 1 and 2 only D. 1, 2 and 3 |
KeywordsHPV Vaccine, Human Papillomavirus, Cervical Cancer, Delhi Health Department, HPV Vaccination Drive, National HPV Programme, Cervical Cancer Prevention, GLOBOCAN 2022, IARC, School Health Programme, Vaccine Hesitancy Focus AreaPrelims Human Papillomavirus (HPV), Cervical Cancer, GLOBOCAN, IARC Mains GS II (Health & Governance), Public health policy, Universal immunisation, Women's health GS III (Science & Technology) Vaccination technology, Biotechnology in public health, Disease prevention, Health awareness and misinformation |
Delhi has launched a renewed 100-day HPV vaccination campaign with a target of vaccinating 1.49 lakh girls (14 years) after reviewing the slow progress of the first phase. The campaign will focus on government schools, awareness drives, parent counselling, and combating vaccine hesitancy to protect girls against cervical cancer.
Although the vaccination programme has been running for over four months, Delhi's progress has remained slower than expected.
Major Reasons :
After schools reopened, the Health Department decided to relaunch the campaign with greater involvement of the Education Department.
The Delhi government is adopting a multi-pronged approach to improve vaccination coverage.
The government is focusing on countering misinformation through :
Officials believe that urban populations like Delhi require stronger communication strategies because health misinformation spreads rapidly through social media.
Human Papillomavirus (HPV) is one of the most common viral infections affecting humans.
Most HPV infections disappear naturally, but persistent infection with high-risk strains can develop into cancer over several years.
The HPV vaccine protects against the high-risk HPV types responsible for cervical cancer.
The vaccine works best before exposure to HPV, which is why it is administered to adolescent girls.
India launched the nationwide programme on 28 February 2026.
Girls aged 14 years
Nearly 1.15 crore girls across India
According to GLOBOCAN 2022 estimates published by the International Agency for Research on Cancer (IARC) :
These figures highlight the importance of both HPV vaccination and regular cervical cancer screening.
Despite the availability of an effective vaccine, several challenges remain :
Public awareness remains one of the most important components of successful vaccination programmes.
Schools provide the most effective platform for adolescent immunisation because they enable :
Delhi's renewed strategy therefore places government schools at the centre of the campaign.
|
Parameter |
Data |
|---|---|
|
Programme Launch |
28 February 2026 |
|
Target Group |
Girls aged 14 years |
|
Delhi Vaccinations So Far |
~13,500 doses |
|
New Delhi Target |
1.49 lakh vaccinations in 100 days |
|
National Annual Target |
1.15 crore girls |
|
Cause of Vaccination |
Prevention of Cervical Cancer |
|
Cervical Cancer Cases in India (GLOBOCAN 2022) |
1.2 lakh+ annually |
|
Cervical Cancer Deaths (India) |
~80,000 annually |
|
Main Challenge |
Vaccine hesitancy & misinformation |
|
Key Implementation Agency |
Delhi Health Department with Education Department |
Practice MCQQ. With reference to Human Papillomavirus (HPV), consider the following statements:
Which of the statements given above is/are correct? A. 1 and 2 only Mains Practice QuestionHow can HPV vaccination contribute to reducing India's cervical cancer burden? Discuss the key challenges in achieving universal vaccine coverage and suggest measures to overcome them. |
Frequently Asked Questions (FAQs)1. What is HPV ?Human Papillomavirus (HPV) is a common viral infection. Persistent infection with high-risk HPV types causes nearly all cases of cervical cancer. 2. Who is eligible under India's HPV vaccination programme ?The programme currently targets 14-year-old girls across the country. 3. Why is the HPV vaccine important ?It protects against high-risk HPV infections and significantly reduces the risk of developing cervical cancer later in life. 4. Why is Delhi relaunching the campaign ?Vaccination progress was slower than expected due to school examinations, summer vacations, and vaccine hesitancy. The renewed campaign aims to accelerate coverage through schools. 5. Which international agency publishes global cervical cancer estimates ?The International Agency for Research on Cancer (IARC) publishes GLOBOCAN, which provides global estimates on cancer incidence and mortality. |
Agriculture in India continues to face several structural challenges, including :
Farm mechanization addresses these issues by enabling timely farm operations, reducing dependence on manual labour and animal power, improving input-use efficiency, lowering production costs, minimizing post-harvest losses, and increasing overall agricultural productivity.
Mechanization also supports climate-resilient agriculture through precision farming technologies such as drones, GPS-enabled equipment, and efficient crop residue management.
The major objectives of the scheme are :
SMAM supports mechanization throughout the crop production cycle by promoting :
The scheme also organizes demonstrations, farmer training, capacity building, and awareness programmes to encourage adoption of modern agricultural technologies.
SMAM provides subsidies for purchasing agricultural machinery through the Direct Benefit Transfer (DBT) system.
Additionally, small and marginal farmers receive ₹2,000 per hectare for accessing mechanized services through Custom Hiring Centres, SHGs, and FPOs, including drone services.
One of the flagship interventions under SMAM is the establishment of Custom Hiring Centres (CHCs).
These centres provide agricultural machinery on rent, allowing farmers to use expensive equipment without purchasing it.
Financial assistance is available up to 40% of project cost for projects costing up to ₹250 lakh.
Farm Machinery Banks are established mainly by :
These institutions collectively own machinery and rent it to farmers.
Financial support under SMAM includes :
SMAM promotes the establishment of Hi-Tech Hubs equipped with advanced machinery such as :
These hubs improve operational efficiency and promote adoption of precision agriculture.
Recognizing low mechanization levels in North-Eastern India, SMAM provides special incentives.
These include :
This reduces regional disparities in access to farm machinery.
SMAM follows a shared funding model.
|
Region |
Funding Pattern |
|
General States |
60:40 (Centre : State) |
|
North-Eastern & Himalayan States |
90:10 |
|
Union Territories |
100% Central Assistance |
This differentiated funding structure enables wider adoption across geographically diverse regions.
Since its launch, SMAM has achieved significant progress.
SMAM actively promotes the use of drones in agriculture to encourage precision farming.
The initiative is implemented in collaboration with :
Between 2023–24 and 2025–26 :
The demonstrations focused on :
SMAM provides financial assistance for drone procurement.
These institutions receive :
FPOs receive :
75% grant assistance for purchasing drones.
Drone service agencies receive :
₹6,000 per hectare as contingency support for providing drone-based agricultural services.
SMAM emphasizes gender inclusion.
30% of the total scheme allocation is earmarked for women farmers.
The objective is to improve women's access to modern agricultural machinery, reduce drudgery, and enhance their participation in mechanized agriculture.
SMAM operates under the umbrella of the Rashtriya Krishi Vikas Yojana (RKVY).
In 2017-18, RKVY was restructured as :
RKVY-RAFTAAR (Remunerative Approaches for Agriculture and Allied Sector Rejuvenation)
The restructured programme emphasizes :
SMAM contributes significantly to India's agricultural transformation.
Despite notable progress, several challenges remain.
To maximize the impact of SMAM, the following measures are essential :
The Sub-Mission on Agricultural Mechanization (SMAM) has emerged as one of India's most important initiatives for modernizing agriculture through inclusive access to farm machinery. By combining financial assistance, Custom Hiring Centres, Farm Machinery Banks, Hi-Tech Hubs, and drone-based precision farming, the scheme has substantially improved mechanization among small and marginal farmers while reducing labour drudgery and enhancing productivity. Going forward, greater emphasis on digital technologies, climate-smart mechanization, indigenous innovation, and last-mile accessibility will be essential to achieving sustainable, efficient, and globally competitive agriculture in line with the vision of Viksit Bharat 2047.
Frequently Asked Questions (FAQs): Sub-Mission on Agricultural Mechanization (SMAM)Q1. What is the Sub-Mission on Agricultural Mechanization (SMAM)?Answer : SMAM is a Centrally Sponsored Scheme launched in 2014–15 under the Rashtriya Krishi Vikas Yojana (RKVY) to promote farm mechanization by improving farmers' access to modern agricultural machinery and equipment.Q2. Which ministry implements the SMAM?Answer : The scheme is implemented by the Ministry of Agriculture and Farmers Welfare, Government of India. |
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